Your contact partners
in this area:
Prof. <br /> Dr. med. habil.<br /> Georg Matziolis
Dr. med. habil.
Georg Matziolis

Senior Consultant of the Clinic for Orthopaedics and Accident Surgery

Acting holder of the Chair for Orthopaedics of the FSU Jena at the Waldkrankenhaus Eisenberg

036691 8-1002

Specialist Registrar Dr. med. Steffen Brodt
Specialist Registrar Dr. med. Steffen Brodt

Head of department hip

Specialist for Orthopaedics and Accident Surgery, Special Orthopaedic Surgery

Bone bank

Specialist services

The Chair for Orthopaedics of the Friedrich Schiller University in Jena at the Waldkrankenhaus Eisenberg has its own bone bank. As the only clinic in Thuringia so far, we have a permit in accordance with §§ 20 b and c (Arzneimittelgesetz = German medicinal products act), which enables the production of the "pharmaceutical bone" by law and permits operation of such a bone bank.

It is managed by Consultant Dr. med. Andreas Wagner. Together with his team, he ensures that enough bones are available to treat bone defects. Operation of such a bone bank enables the bones of a person to be transferred to another, as also occurs, for example, with blood supplies.

Advantages of the hospital's own bone bank

Accidents, bone diseases and also loosening of artificial joints may lead to bone defects, which must be filled in or bridged with revision operations.

The operative reconstruction of bone defects by filling can in principle be carried out with bone transplants of bones from the own body or other people's bodies or even animal bone transplants or with synthetic bone replacement materials. Own bone donation, to be regarded as the most favourable method in terms of healing of the transplant (own donation, for example with an iliac crest cancellous bone transplant) is limited above all by the limited quantity of available bone and has the further disadvantage of additionally necessary operative exposure at the place of donation (iliac crest).

Established method for major bone defects

Due to the limited availability, it is necessary to resort to transplants of bones from other persons or bone replacement materials. The term "allogenic bone transplant" describes the method of transferring bones from one individual to another of the same type (i.e. from human to human). This is to be distinguished from xenogenous (foreign to the species) transplantation (for example from cattle). The process-specific residual infection risk which arises here, problems of immunogenicity and the rejection reaction as well as the generally low acceptance by recipients and the transplanting doctor, restrict the use of xenogenous transplants. Therefore, in the last few decades, allogenous bone transplantation (transfer from human to human) has developed into an established and essential part of treatment of major bone defects.

To top

As the only clinic in Thuringia, the Waldkrankenhaus Eisenberg has permission to operate a bone bank.

As the only clinic in Thuringia, the Waldkrankenhaus Eisenberg has permission to operate a bone bank.

Quality Assurance

To protect the recipient, the "Richtlinien zum Führen einer Knochenbank" (German bone banking guidelines) were published in Germany in 1996, the revision of which from 2001 until today forms the basis of medical actions when operating a bone bank. These guidelines govern the recognised requirements for selection of donors, quality assurance measures and concrete procedural instructions for as safe as possible handling of bone transplants. In accordance with the EC Directive 2004/23/EC, quality and safety standards for the donation ... processing ... distribution of human tissue …" were defined, which we verifiably meet in the management of our clinic's own bone bank as a pre-requisite for the licence in accordance with §§ 20 b and c (Arzneimittelgesetz). (Date: November 2009).

To top